detection icon

Short bio

Protect - Your - Systems - Amigo

PYSA is short for Protect – Your – Systems – Amigo



Victims will find the ransom note called Readme.README

PYSA ransom note

Type and source of infection

Ransom.Mespinoza is ransomware. Ransomware in general makes files on the victims system unusable until the ransom is payed. Ransom.Mespinoza is believed to be spread using RDP brute force attacks. Once a network is breached it uses tools like mimikatz and psexec for lateral movement.


Malwarebytes protects business and home users from Ransom.Mespinoza by using Anti-Ransomware technology and real-time protection.

Malwarebytes blocks Ransom.Mespinoza

Home remediation

Malwarebytes can detect and remove Ransom.Mespinoza without further user interaction.

  1. Please download Malwarebytes to your desktop.
  2. Double-click MBSetup.exe and follow the prompts to install the program.
  3. When your Malwarebytes for Windows installation completes, the program opens to the Welcome to Malwarebytes screen.
  4. Click on the Get started button.
  5. Click Scan to start a Threat Scan.
  6. Click Quarantine to remove the found threats.
  7. Reboot the system if prompted to complete the removal process.

Take note, however, that removing this ransomware does not decrypt your files. You can only get your files back from backups you made before the infection happened.

Business remediation

How to remove Ransom.Mespinoza with the Malwarebytes Nebula console

You can use the Malwarebytes Anti-Malware Nebula console to scan endpoints.

endpoint menu

Nebula endpoint tasks menu

Choose the Scan + Quarantine option. Afterwards you can check the Detections page to see which threats were found.

Nebula detections

On the Quarantine page you can see which threats were quarantined and restore them if necessary.

Nebula Quarantaine

All component/technology detections are passed to the remediation engine for complete removal from infected systems. This industry leading technology uses patented techniques in identifying all cohorts or associated files for a single threat and removes them all together to prevent malware from resuscitating itself. If you are using Malwarebytes Ransomware Rollback technology, it allows you to wind back the clock to negate the impact of ransomware by leveraging just-in-time backups.


  • 7fd3000a3afbf077589c300f90b59864ec1fb716feba8e288ed87291c8fdf7c3

  • e4287e9708a73ce6a9b7a3e7c72462b01f7cc3c595d972cf2984185ac1a3a4a8

  • 327934c4c11ba37f42a91e1b7b956d5a4511f918e63047a8c4aa081fd39de6d9